SIMRbase Organisms

The sea lamprey is a member of an ancient lineage that diverged from the vertebrate stem approximately 550 million years ago (MYA). By virtue of this deep evolutionary perspective, lamprey has served as a critical model for understanding the evolution of several conserved and derived features that are relevant to broad fields of biology and biomedicine. Studies have used lampreys to provide perspective on the evolution of developmental pathways that define vertebrate embryogenesis, vertebrate nervous and neuroendocrine systems, genome structure, immunity, clotting and others. These studies reveal aspects of vertebrate biology that have bee... [more]

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